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Modules
Mathematics
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Mathematics |
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MathematicsApplied Mathematics I
differential and integral calculus for functions with more than one variable, nonlinear differential equations, partial differential equations, Green-functions Applied Mathematics II
scalar fields and vector fields, vector analysis, integral theorems, eigenvalue problems, numerical mathematics, optimization Applied Statistics
Revision of basic statistical concepts – hypotheses, data exploration, central tendency and spread, normal distribution, robust measures Sampling design – population, sample, unit, simple/stratified random sample, undercoverage, nonresponse, response bias Experimental design – factor, control group, placebo effect, randomization, bias, single/double-blind, matching, blocking Confidence intervals, sample vs population statistics, standard error Significance testing for a difference in mean (normal data), choosing a sample size, power Correlation and regression Non-normal distributions, non-parametric significance testing Comparing two proportions, two-way tables, chi-squared test ANOVA, main effect, interaction, masking. F statistic False positives, false negatives, sensitivity and specificity, how a good treatment can appear to be paradoxically bad Visualization of statistical datasets |
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Medicine
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Medicine |
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MedicineSelected Topics in Medicine for Medical Engineers I
Selected topics in medicine (e.g. sense organs, muscular system) according to medical devices for diagnosis and rehabilitation – part 1. Selected Topics in Medicine for Medical Engineers II
Selected topics in medicine (e.g. sense organs, muscular system) according to medical devices for diagnosis and rehabilitation – part 2. |
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Advanced Medical Imaging and Diagnosis Systems
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Advanced Medical Imaging and Diagnosis Systems |
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Advanced Medical Imaging and Diagnosis SystemsAdvanced Medical Imaging and Diagnosis Systems I
Photoacoustic Imaging (PAI), Optical Coherence Tomography (OCT), Diffuse optical imaging, Infrared Spectroscopy (IR) functional and multimodal imaging (fMRI, parallel MRI, PET-CT, MR-PET) - part 1 Advanced Medical Imaging and Diagnosis Systems II
functional and multimodal imaging - part 2 special topics in x-ray imaging, nuclear medicine and sonography radiation protection (dosimetry, instrumentation, measures for radiation protection) |
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Bionic Implants
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Bionic Implants |
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Bionic ImplantsBionic Implants I
physiology of hearing; signal processing of acoustic signals; cochlea implants; study design for human studies Bionic Implants II
background of myoelectric prostheses; signal analysis of EMG-signals, simple machine learning for prosthesis control |
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Clinical Treatment Systems
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Clinical Treatment Systems |
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Clinical Treatment SystemsClinical Treatment Systems
electro surgery, deep brain stimulation, navigation systems (cranial, spine, orthopaedic, ENT, Hip), computer assisted surgery, robotic systems for surgery, training systems for surgery, interventional radiology (stenting, coiling,…), endoscopy, hybrid OR and intraoperative imaging, stereotactic radio surgery, awake surgery, CAD-CAM cranioplasty |
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Technological Innovation in Medicine
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Technological Innovation in Medicine |
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Technological Innovation in MedicineTechnological Innovation in Medicine I
Current topics in biomedical engineering. Technological Innovation in Medicine II
Students face innovation areas based on selected research activities in our TIMed Center of Excellence. In practical group exercises research in appropriate sources like scientific databases, journals or conference proceedings is done to explore new fields of knowledge independently and utilize them for the development of innovative ideas. |
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Electronics
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Electronics |
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ElectronicsElectronic Circuit Design
Design of complex analog circuits, alternative circuit topologies and technologies, Circuit simulation including parameter variation, Circuit prototyping and testing Rail2Rail, Switched Capacitor, Current-Mode, Oscillator Elaboration of circuits / schematics e.g. from literature and build-up or simulate circuits in the LAB Embedded Systems I
Induction, Transformer Main Equation, Analog- and Digital Power Supply, Mixed Signals (DC-, AC-Components, Correlation), Pulse Width Modulation (PWM), Class-D-Amplifier, Complex Signals in the Time-and Frequency Domain, Modulation, High-Frequency Embedded Systems II
CPU selection: μP – Signalprocessor, Families and derivates, Power sav-ing modes, Supervisory circuits: Power and Watchdogs (SW and HW), Interfaces to analog circuits, Digital interfaces: bus interface timing, transmission lines, wireless, FPGA Design and implementation, IP-cores, VHDL, Programming Tools and verification Power Supply Systems
Power – Up sequence (Soft-Key, Stand-By), Power Down sequence, Power line supplies: switched mode, wideband; DC-DC-Converter, Battery supplies: charging, regulating, Low Bat – supervision, Energy Harvesting |
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Biomechanics
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Biomechanics |
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Biomechanics3D Motion Capture and Analysis
Vectors in 3D, Coordinate Systems, Transformation (Rotation) Matrices, Euler Angles, Quaternions, Velocity Vector (Translation and Rotation), Acceleration Vectors, Movement analysis with data from optical systems and from IMUs, Data analysis with Python Musculoskeletal Systems Modeling and Simulation
Modelling of the Skeletal System: minimal and generalized coordinates, body-fixed and inertial reference frames, transformation matrices, Euler parameters, angular velocity tensor, principle of linear momentum, principle of conservation of angular momentum, formulation in inertial and body-fixed reference frames, inertia tensor, tensor transformation, equations of motion for multi-body systems, projection equation. Simulation of the Musculoskeletal System: Inverse kinematics problem, constraint optimization, inverse dynamics, computed torque control, computed muscle control. Biomechanical Laboratory
Introduction to the modelling and simulation of the musculoskeletal system with MatLab and OpenSim, Biomechanical Laboratory with application of different 3D motion tracking systems, motion analysis, muscle activation measurement and application of inverse kinematics, inverse dynamics and computed muscle control. Numerical Methods in Biomechanics
Part 1: Numerical solution of partial differential equations: Differencing schemes, Finite Difference Method, stability analysis, Finite Element Method Part 2: Transport mechanisms and physical principles: Fick’s law, continuity-equation, diffusion, filtration, convection, diffusion-convection, Navier-Stokes equations, dimensionless representations, Reynolds number, Peclet number Part 3: Application to practical examples: nutrient transport into vertebral disk by diffusion, stationary and in-stationary blood flow simulation around a stenosis, blood flow simulation in an aneurysm, convection-diffusion simulation of drug eluting stents, convection-diffusion simulation of contrast agent in Angiography |
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Medical Device Software
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Medical Device Software |
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Medical Device SoftwareApplied Programming I
Software-Design-Methods for low-level programming (time-triggered-systems, event-triggered-systems), digital Interfaces, timer, interrupts, watchdog, realtime-systems. Applied Software Life Cycle Processes
EN ISO 62304 under consideration of EN ISO 14971 and IEC/TR 80002 incl. safety classification, V-model and Agile Models (SCRUM), automated software tests: planning and reporting, traceability, IEC 82304 health software validation, software architecture (component, module, system), MDR rule 11 Applied Programming II
TCP (Transmission Control Protocol) and UDP (User Datagram Protocol) for medical data transfer and data processing via medical IT networks. Artificial Intelligence
Advantages in applying AI methods, Methods of Artificial Intelligence (e.g. Deep Learning, Machine Learning, Neural Networks), supervised Learning and Acceptance Criteria in Medicine and Medical Device Technologies, Approval Criteria |
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Materials Technology
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Materials Technology |
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Materials TechnologyAdvanced Materials
from microphysics to nanophysics, scaling and the limits of miniaturization, making of nanostructures (top-down and bottom-up), nano architectures (particles, tubes, film systems, colloidal), sol-gel technology, nano imprint lithography, nano particle assays, microfluidics Molecular Test Systems
lecture: gene expression (from DNA to protein), recombinant plasmid technology (cloning vectors, protein production, antibody production, reporter gene systems, in vitro transcription assays, transfection, evidence of gene expression, molecular sensing methods (ELISA, FACS, FCS, AFM, SDT, FISH, α-Screen-Technology), Introduction to Biosafety Levels lab work: detection methods at various levels: microscopy (fusion proteins), ELISA (antigene-antibody-interaction), Introduction to cell culture, Western-Blot (protein-antibody-interaction), PCR (RT-PCR) test systems for detecting microorganisms and viruses Surface Technology
scale dependency of surface effects, surface properties (surface tension, capillary effects, surface activity, colloid systems, adsorption, physisorption, chemisorption, catalyst activity), surface pretreatment, activation and modification, thin film technologies (PVD, CVD, surface finishing, functionalization, self-assembling, plasma treatment) |
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Applied Systems Engineering
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Applied Systems Engineering |
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Applied Systems EngineeringApplied Systems Engineering
System engineering process, system design in time and frequency domain, reliability, safety, maintainablity, linear- and nonlinear distortions, analog-to-digital-conversion, noise, oversampling quadrature modulation, scattering matrix, smith card, state-of-the-art (EN ISO 60601, et al), bringing medical systems into being, patents |
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Requirements and Usability Engineering
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Requirements and Usability Engineering |
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Requirements and Usability EngineeringRequirements and Usability Engineering
Requirements analysis and engineering, design for testability, usability engineering process (EN ISO 62366), interface design, hardware and software usability concepts considering patients, users and third parties. |
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International Product Management
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International Product Management |
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International Product ManagementInternational Product Management
Product management in international markets. How do regulatory affairs influence product strategy planning? Where / how is “Europe” different to the US and other markets? Fundamentals in international marketing and sales. Analysis of competition. Submissions. |
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Regulatory Affairs
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Regulatory Affairs |
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Regulatory AffairsRegulatory Affairs
European, US market and others. Principles of and differences in approval processes; EU: MDR/IVDR+MDCG Documents, FDA, Preparing Audits, Documentation |
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Project
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Project |
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ProjectProject: Scientific or Professional
The project can be performed within current research projects of the degree program and/or in cooperation with external partners (industry, healthcare institutions or research institutions), supervision by teaching staff of the degree program. |
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Master Thesis
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Master Thesis |
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Master ThesisMaster Examination
Master Thesis
Autonomous planning and realization of the master thesis on a subject in the field of medical engineering. Supervision by teaching staff of the degree program. |
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German Language
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German Language |
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German LanguageGerman Language I A1.1.
German Language German Language II A1.2.
German Language |
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Introduction to Programming-Tools
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Introduction to Programming-Tools |
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Introduction to Programming-ToolsIntroduction to Programming-Tools
Introduction to new IDE’s (Integrated Development Environments) and systematic implementation of algorithmic solutions for selected problems in medical engineering by means of scientific programming languages (e.g. MATLAB, Scientific Python, C). |
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Cellular Biophysics
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Cellular Biophysics |
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Cellular BiophysicsCellular Biophysics
Composition and Function of Cell Membranes; History and Traditional Techniques of Studying the Structure of Cell Membranes; The Biophysics of Cell Membranes, Cell Surface Diffusion, Adsorption, Interaction and Transport of Nanoparticles (Drugs, Virus, Biomolecules); Quantum Mechanics of the Cell; Practical exercise: Biophysical description of cellular processes using learned theoretical models and practical visualisation of cellular processes. |
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